Probilim® Daily (Probiotic + Prebiotic)

• Preventing or reducing the duration and severity of various types of diarrhea, including antibiotic-associated diarrhea, Clostridium difficile diarrhea, traveler’s diarrhea and rotaviral diarrhea.
• Improving the symptoms of irritable bowel syndrome (IBS) such as reducing abdominal pain, bloating, constipation, frequent bowel movements and improving stool consistency.
• Reducing symptoms of IBD such as ulcerative colitis, preventing the relapse of disease and helping in the treatment of chronic pouchitis.
• Increasing the synthesis of folic acid and vitamins B2, B3, B6 and B12.
• Improving the digestion and absorption of nutrients such as proteins and fats.
• Improving the cardiovascular diseases including high blood cholesterol and hypertension. Probiotics and prebiotics can decrease the blood pressure, blood total cholesterol, LDL and triglyceride and can increase the blood level of HDL.
• Helping with digestion of lactose in people with lactose intolerance.
• Preventing and controlling hyperglycemia (high blood glucose) in people with diabetes (helping in the reduction of fasting blood glucose and insulin resistance).
• Helping decrease of hepatic aminotransferase enzymes, total cholesterol and insulin resistance in patients with nonalcoholic fatty liver.
• Helping control of celiac disease by digesting gluten polypeptides and exert protective effects on epithelial cells.

Contraindication
Avoid taking this product if you have acute pancreatitis or have a history of allergy.

How to Use
Take 1 or 2 capsules daily with water on an empty stomach (1 hour before meal) or as directed by your doctor.

Pharmacological and Clinical Effects
The human gastrointestinal tract is colonized with a diverse population of microbes (microbial flora). This microbial flora not only has digestive function but also contributes in the homeostasis of intestinal epithelium and innate immunity. This microflora’s change is effective in the pathogenesis of various diseases, such as infections, inflammations, allergies and immunologic disorders. Recognition of the importance of intestinal microflora has increased the use of probiotics for promoting and maintaining overall health. Probiotics are defined as live microorganisms which when administered in adequate amounts, confer a health benefit on the host. Lactobacillus and Bifidobacterium are the most common probiotic strains. Streptococcus thermophilus and Saccharomyces boulardii are also used as probiotics.

Prebiotics are supplements that are not hydrolyzed and absorbed in the small intestine and are available as food for colon microflora and selectively stimulate the growth and activity of a number of bacterial species of gastrointestinal flora, thus have beneficial effects on the health of the host. The most commonly used prebiotics are carbohydrates with different sizes and of all types of them, fructooligosaccharide and inulin can be mentioned.

Probılım Daily® containing high amounts of 9 effective strains of bacteria and FOS prebiotic and a renovated formulation, is the best choice for providing daily probiotic requirements of family members. This product improves gastrointestinal function and adjusts the immune system by remaking digestive normal flora. Probilim Daily ® is effective in preventing and reducing the duration of antibiotic-associated diarrhea, travelers’ diarrhea and viral diarrhea. It is also effective in improving the symptoms of IBS, IBD and lactose intolerance.

Side Effects
The probiotics of this product are all safe, most are registered as GRAS agents (Generally Recognized as Safe) by the US Food and Drug Administration (FDA) and the rest are approved by Europe and Japan. Probiotics are well tolerated and can only produce bloating in some patients, which usually improves with continued use. If this complication persists or worsens, inform your doctor or pharmacist.

Use With Other Drugs
Concomitant use of antibiotics with probiotics might decrease the effectiveness of probiotics. So it is recommended to take these two drugs with at least two hours interval.

Precaution and Warning
In the following cases, inform the physician before taking this product:

Having special conditions such as immunodeficiency and AIDS, taking immunosuppressive drugs and chemotherapy drugs, using intravenous catheters, heart valve disease, active ulcerative colitis, short bowel syndrome, signs of infection (such as fever, vomiting, bloody diarrhea and severe abdominal pain), any history of medicine or food allergies.

Inform your doctor or pharmacist immediately if you notice any signs of infection (such as high fever, chills and persistent cough) or allergic reaction such as skin rash, itching, hives, swelling of the face, severe dizziness, cough, tightness in the chest and trouble in breathing.

Pregnancy and Lactation
Based on scientific studies, the use of probiotics is safe during pregnancy and lactation, but it’s best to take it with your doctor’s advice.

Storage
Keep it below 25 °C, away from moisture and direct sunlight.

This is not a drug.

Keep out of sight and reach of children.